Calculate required sample size for clinical trials with adjustments for dropout rates.

Calculate CIs for means, proportions, differences, odds ratios, and relative risks

Calculate Number Needed to Treat and Number Needed to Harm

Generate block randomization sequences for clinical trials with reproducible seeds

Grade adverse events using CTCAE v5.0 criteria with this searchable reference tool.

Convert between ECOG and Karnofsky performance status scales

Causality assessment for adverse drug reactions using the Naranjo Algorithm

Classify and assess protocol deviations with severity ratings and reporting requirements

Calculate BSA using multiple validated formulas for drug dosing in clinical trials.

Estimate renal function using Cockcroft-Gault, MDRD, CKD-EPI 2009, and CKD-EPI 2021 equations

Calculate IBW using Devine, Robinson, Miller, and Hamwi formulas

Calculate corrected QT interval using Bazett, Fridericia, Framingham, Hodges, and Rautaharju formulas

Calculate pediatric doses using Clarks, Youngs, Frieds rules and BSA-based methods

Calculate protocol visit windows and validate visit dates against schedule

Calculate regulatory reporting deadlines for serious adverse events

Plan clinical trial timelines with milestone dependencies and critical path analysis